CCDC138

Across TCGA patient cohorts, CCDC138 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,050 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC138-associated proteins across cancer lineages are TRIM33, SMC2, and SSB. Each is linked with CCDC138 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCDC138-to-partner and partner-to-CCDC138 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC138 versus TRIM33 in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC138→partner) and Y-score (partner→CCDC138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM33 →	+0.396	+0.636	<.001	<.001	3	8
LUAD	SMC2 →	+0.651	+0.660	<.001	<.001	3	8
LSCC	SSB →	+0.334	+0.636	<.001	<.001	3	8
GBM	ADNP →	+0.388	+0.628	<.001	<.001	3	8
GBM	IWS1 →	+0.321	+0.536	<.001	<.001	3	8
OV	WDHD1_S407 →	+0.897	+0.606	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,050 associations by consensus.

CCDC138 vs TRIM33 — GBM

Explore this scatter interactively →