CCDC138

Across TCGA patient cohorts, CCDC138 protein abundance is significantly associated with the RNA expression of many other genes, with 2,732 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC138-associated genes across cancer lineages are WDR77, ELP6, and ITPRIP-AS1. Each is linked with CCDC138 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC138-to-partner and partner-to-CCDC138 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC138 versus WDR77 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC138→partner) and Y-score (partner→CCDC138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR77 →	+0.857	+0.529	<.001	.001	3	3
LSCC	ELP6 →	+0.445	+0.527	.006	.007	3	2
LSCC	ITPRIP-AS1 →	-0.947	-0.656	.003	.008	3	2
UCEC	KIF9 →	+0.621	+0.413	<.001	<.001	3	2
UCEC	LIX1 →	-1.167	-0.510	.003	.001	3	2
LUAD	ACYP2 →	-0.746	-1.034	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,732 associations by consensus.

CCDC138 vs WDR77 — UCEC

Explore this scatter interactively →