CCDC138

Across TCGA cell cohorts, CCDC138 mutation is significantly associated with the drug of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC138-associated genes across cancer lineages are SGC-CBP30, Dactinomycin, and 123829. Each is linked with CCDC138 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC138-to-partner and partner-to-CCDC138 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGC-CBP30 grouped by CCDC138-low versus CCDC138-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC138→partner) and Y-score (partner→CCDC138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SGC-CBP30 →	+0.340	+2.649	.015	.046	3	1
LARGE_INTESTINE	Dactinomycin →	+0.569	+2.649	.014	.046	3	1
LARGE_INTESTINE	123829 →	+0.602	+2.649	.039	.046	3	1
LARGE_INTESTINE	IC-87114 →	+0.254	+2.652	.013	.045	3	1
LARGE_INTESTINE	GSK1059615 →	+0.568	+2.652	.016	.045	3	1
LARGE_INTESTINE	ETP-45835 →	+0.289	+2.652	.016	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

SGC-CBP30 by CCDC138 expression — LARGE_INTESTINE

Explore this box plot interactively →