CCDC13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC13 mutation is significantly associated with the RNA expression of many other genes, with 4,225 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC13-associated genes across cancer lineages are RN7SL339P, GLRX5, and EIF4A3. Each is linked with CCDC13 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC13-to-partner and partner-to-CCDC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL339P grouped by CCDC13-low versus CCDC13-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC13→partner) and Y-score (partner→CCDC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRN7SL339P →+0.190+3.785<.001.00433
UCECGLRX5 →+0.353+2.032.004.00533
SKCMEIF4A3 →+0.532+2.826.001.00133
LIHCOOEPP1 →+0.089+3.413<.001.00732
LIHCMIR6796 →+0.354+3.853<.001.00332
READIGHD5-12 →+1.742+5.421<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,225 associations by consensus.

RN7SL339P by CCDC13 expression — LUSC

Box plot of RN7SL339P in CCDC13-low vs CCDC13-high samples in LUSC.

Explore this box plot interactively →

Exploration