CCDC13

Across TCGA cell cohorts, CCDC13 mutation is significantly associated with the drug of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC13-associated genes across cancer lineages are Sabutoclax, KRAS (G12C) Inhibitor-12, and Temsirolimus. Each is linked with CCDC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC13-to-partner and partner-to-CCDC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sabutoclax grouped by CCDC13-low versus CCDC13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC13→partner) and Y-score (partner→CCDC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Sabutoclax →	+0.544	+2.991	.005	.018	3	2
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.697	+2.868	.002	.022	3	2
LARGE_INTESTINE	Temsirolimus →	+0.453	+2.649	.049	.046	3	1
LARGE_INTESTINE	Lestaurtinib →	+0.655	+2.710	.007	.043	3	1
LARGE_INTESTINE	5-Fluorouracil →	+0.562	+2.991	.041	.018	3	1
LARGE_INTESTINE	MK-1775 →	+0.313	+2.868	.043	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Sabutoclax by CCDC13 expression — LARGE_INTESTINE

Explore this box plot interactively →