CCDC126

Across TCGA patient cohorts, CCDC126 protein abundance is significantly associated with the RNA expression of many other genes, with 3,160 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC126-associated genes across cancer lineages are POU2AF1, PIM2, and ARL4A. Each is linked with CCDC126 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC126-to-partner and partner-to-CCDC126 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC126 versus POU2AF1 in HNSC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC126→partner) and Y-score (partner→CCDC126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POU2AF1 →	-1.938	-0.648	<.001	.002	3	3
LUAD	PIM2 →	-1.157	-0.386	<.001	.002	3	2
LUAD	ARL4A →	+1.634	+0.399	<.001	.004	3	2
COAD	WDFY4 →	-0.828	-0.515	<.001	.006	3	2
LUAD	STAB2 →	-0.555	-0.273	.003	.002	3	2
UCEC	RNF38 →	-0.615	-0.440	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,160 associations by consensus.

CCDC126 vs POU2AF1 — HNSC

Explore this scatter interactively →