Across TCGA pan-cancer cohorts, CCDC121P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CCDC121P1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CCDC121P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC121P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
HNSC, KIRC, and LUSC are the cancer types where CCDC121P1 tumor–normal differential expression is most reproducible.