CCDC121

Across TCGA pan-cancer cohorts, CCDC121 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC121 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC121 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC121 expression acts as an unfavorable survival marker.

CCRCC, LUAD, and LSCC are the cancer types where CCDC121 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.399	0.932	.022	25	view →
LUAD	DFS	Quartile	II,III,IV	0.689	0.927	.011	5	view →
LSCC	DFS	Median	II,III,IV	0.553	0.822	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCDC121–CCRCC (DFS)

Open the CCRCC breakdown →