CCDC121

Across TCGA patient cohorts, CCDC121 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,499 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC121-associated proteins across cancer lineages are THEMIS2, BROX, and C5AR1_S327. Each is linked with CCDC121 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC121-to-partner and partner-to-CCDC121 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC121 versus THEMIS2 in LSCC, with a Pearson correlation of -0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC121→partner) and Y-score (partner→CCDC121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THEMIS2 →	-0.418	-0.533	<.001	<.001	3	6
HNSC	BROX →	+0.309	+0.470	<.001	<.001	3	6
GBM	C5AR1_S327 →	-1.023	-0.311	.001	.009	3	6
BRCA	NCF2 →	-0.526	-0.617	<.001	<.001	3	6
BRCA	FERMT3 →	-0.534	-0.495	<.001	.002	3	6
BRCA	RO60 →	+0.263	+0.468	<.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,499 associations by consensus.

CCDC121 vs THEMIS2 — LSCC

Explore this scatter interactively →