CCDC12

Across TCGA patient cohorts, CCDC12 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,221 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC12-associated proteins across cancer lineages are QRICH1, RBM15B, and DHX30. Each is linked with CCDC12 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC12-to-partner and partner-to-CCDC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC12 versus QRICH1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC12→partner) and Y-score (partner→CCDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	QRICH1 →	+0.266	+0.300	<.001	<.001	3	6
GBM	RBM15B →	+0.233	+0.215	<.001	<.001	3	5
LSCC	DHX30 →	+0.281	+0.307	<.001	<.001	3	5
LSCC	DCAF1 →	+0.281	+0.188	<.001	.007	2	5
OV	PTPN23 →	+0.183	+0.301	<.001	.001	3	4
GBM	PBRM1 →	+0.314	+0.225	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,221 associations by consensus.

CCDC12 vs QRICH1 — GBM

Explore this scatter interactively →