CCDC12

Across TCGA patient cohorts, CCDC12 protein abundance is significantly associated with the RNA expression of many other genes, with 15,018 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC12-associated genes across cancer lineages are CLK2, TSEN2, and ZNF740. Each is linked with CCDC12 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC12-to-partner and partner-to-CCDC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC12 versus CLK2 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC12→partner) and Y-score (partner→CCDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CLK2 →	+0.469	+0.251	<.001	<.001	3	7
LSCC	TSEN2 →	+0.466	+0.259	<.001	<.001	3	7
HNSC	ZNF740 →	+0.453	+0.271	.002	<.001	3	6
LSCC	USP21 →	+0.476	+0.234	<.001	<.001	3	6
GBM	CHTOP →	+0.446	+0.478	<.001	<.001	3	6
COAD	SLC25A38 →	+0.447	+0.344	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,018 associations by consensus.

CCDC12 vs CLK2 — LSCC

Explore this scatter interactively →