CCDC117

Across TCGA patient cohorts, CCDC117 protein abundance is significantly associated with the RNA expression of many other genes, with 4,199 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC117-associated genes across cancer lineages are NCAPG, MKI67, and GTSE1. Each is linked with CCDC117 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC117-to-partner and partner-to-CCDC117 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC117 versus NCAPG in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC117→partner) and Y-score (partner→CCDC117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPG →	+0.904	+0.305	.004	.001	2	4
OV	MKI67 →	+1.146	+0.250	.005	.003	3	3
GBM	GTSE1 →	+0.984	+0.468	.006	.004	3	3
UCEC	NDC80 →	+0.871	+0.344	<.001	<.001	3	3
UCEC	CDC45 →	+1.024	+0.321	<.001	<.001	3	3
LUAD	SPATS2 →	+0.408	+0.194	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,199 associations by consensus.

CCDC117 vs NCAPG — UCEC

Explore this scatter interactively →