CCDC117

Across TCGA cell cohorts, CCDC117 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,546 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC117-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Regulation of T cell proliferation, and Defense response to bacterium. Each is linked with CCDC117 in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC117-to-partner and partner-to-CCDC117 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by CCDC117-low versus CCDC117-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC117→partner) and Y-score (partner→CCDC117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein localization to condensed chromosome →	+0.125	+0.875	.006	.003	2	13
OVARY	Regulation of T cell proliferation →	-0.100	-0.663	.003	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.112	-0.726	.004	.005	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.074	+0.993	<.001	<.001	3	12
OVARY	Regulation of RNA export from nucleus →	+0.116	+0.863	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.142	+1.099	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,546 associations by consensus.

Protein localization to condensed chromosome by CCDC117 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →