CCDC112

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC112 protein abundance is significantly associated with the RNA expression of many other genes, with 185 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC112-associated genes across cancer lineages are ABHD4, GMPR2, and SALL4. Each is linked with CCDC112 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC112-to-partner and partner-to-CCDC112 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC112 versus ABHD4 in GBM, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC112→partner) and Y-score (partner→CCDC112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMABHD4 →-0.658-0.496.002.00131
GBMGMPR2 →-0.190-0.441.009.00531
GBMSALL4 →+1.130+0.509.005.00931
GBMZNF423 →-1.238-0.593.009<.00131
GBMNHP2P1 →-1.196-0.574.009<.00131
GBMEIF3A →-0.406-0.551.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 185 associations by consensus.

CCDC112 vs ABHD4 — GBM

Per-sample scatter of CCDC112 vs ABHD4 in GBM (Pearson r = -0.64).

Explore this scatter interactively →

Exploration