CCDC112

Across TCGA cell cohorts, CCDC112 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,744 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC112-associated GO terms across cancer lineages are Protein localization to non-motile cilium, Centrosome cycle, and Establishment of mitochondrion localization. Each is linked with CCDC112 in more than 10 cancer types. Because this analysis shows association rather than direction, both CCDC112-to-partner and partner-to-CCDC112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to non-motile cilium grouped by CCDC112-low versus CCDC112-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC112→partner) and Y-score (partner→CCDC112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein localization to non-motile cilium →	+0.082	+1.464	<.001	.006	3	11
URINARY_TRACT	Centrosome cycle →	+0.070	+1.174	.002	.001	3	9
URINARY_TRACT	Establishment of mitochondrion localization →	+0.108	+0.907	.001	.005	3	8
LUNG_SCLC	Regulation of microtubule cytoskeleton organization →	+0.057	+0.657	.004	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of centrosome duplication →	+0.055	+0.718	.001	<.001	3	8
SKIN	Interkinetic nuclear migration →	+0.088	+0.859	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,744 associations by consensus.

Protein localization to non-motile cilium by CCDC112 expression — LIVER

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