CCDC105

Across TCGA patient cohorts, CCDC105 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,776 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CCDC105-associated GO terms across cancer lineages are Axon extension, Peptide transport, and Hematopoietic progenitor cell differentiation. Each is linked with CCDC105 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC105-to-partner and partner-to-CCDC105 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axon extension grouped by CCDC105-low versus CCDC105-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC105→partner) and Y-score (partner→CCDC105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Axon extension →	+0.044	+0.150	<.001	<.001	3	10
STAD	Peptide transport →	+0.032	+0.135	<.001	<.001	3	10
STAD	Hematopoietic progenitor cell differentiation →	+0.056	+0.125	<.001	<.001	3	10
STAD	Negative regulation of cell projection organization →	+0.043	+0.140	<.001	<.001	3	10
STAD	Regulation of extent of cell growth →	+0.039	+0.133	<.001	<.001	3	9
STAD	Receptor-mediated endocytosis →	+0.048	+0.131	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,776 associations by consensus.

Axon extension by CCDC105 expression — STAD

Explore this box plot interactively →