CCDC105

Across TCGA cell cohorts, CCDC105 RNA expression is significantly associated with the mutation status of many other genes, with 79 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCDC105-associated genes across cancer lineages are TNS1, SIN3B, and SYT14. Each is linked with CCDC105 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC105-to-partner and partner-to-CCDC105 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNS1 grouped by CCDC105-low versus CCDC105-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC105→partner) and Y-score (partner→CCDC105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TNS1 →	+4.029	+0.008	.007	<.001	3	2
PANCREAS	SIN3B →	+4.614	+0.010	.004	<.001	3	1
PANCREAS	SYT14 →	+4.614	+0.010	.004	<.001	3	1
PANCREAS	RBM47 →	+5.614	+0.013	.002	<.001	3	1
PANCREAS	GLDC →	+5.614	+0.013	.002	<.001	3	1
PANCREAS	NPIPB5 →	+4.029	+0.008	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

TNS1 by CCDC105 expression — PANCREAS

Explore this box plot interactively →