CCDC103

Across TCGA pan-cancer cohorts, CCDC103 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC103 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CCDC103 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC103 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LIHC, PRAD, and COAD are the cancer types where CCDC103 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.044	0.553	<.001	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
COAD	DFS	Median	All	0.273	0.690	.023	6	view →
SKCM	DFS	Median	II,III,IV	0.198	0.690	.040	3	view →
UCEC	OS	Median	All	1.000	0.654	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC103–LIHC (DFS)

Open the LIHC breakdown →