CCDC102A

Across TCGA patient cohorts, CCDC102A mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC102A-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, Ku80, and MEK1. Each is linked with CCDC102A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC102A-to-partner and partner-to-CCDC102A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by CCDC102A-low versus CCDC102A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC102A→partner) and Y-score (partner→CCDC102A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.500	+2.817	.042	.036	3	1
UCEC	Ku80 →	+0.283	+2.472	.013	.011	3	1
UCEC	MEK1 →	+0.633	+3.459	<.001	.005	2	2
UCEC	p62 Lck ligand →	+0.530	+3.169	<.001	.018	3	1
UCEC	PDCD4 →	-0.463	-2.459	.041	.020	3	1
UCEC	Caspase-7-cleavedD198 →	+0.858	+3.584	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Acetyl-a-Tubulin-Lys40 by CCDC102A expression — UCEC

Explore this box plot interactively →