CCDC102A

Across TCGA cell cohorts, CCDC102A mutation is significantly associated with the RNA expression of many other genes, with 597 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC102A-associated genes across cancer lineages are ZIC5, PHOX2B, and IRX4. Each is linked with CCDC102A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC102A-to-partner and partner-to-CCDC102A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC5 grouped by CCDC102A-low versus CCDC102A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC102A→partner) and Y-score (partner→CCDC102A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZIC5 →	+1.187	+3.628	<.001	<.001	3	2
BLOOD_Leukemia	PHOX2B →	+0.017	+3.365	<.001	.005	3	1
BLOOD_Leukemia	IRX4 →	+0.105	+4.111	.004	.001	3	1
BLOOD_Leukemia	APOL5 →	+0.017	+3.890	<.001	<.001	3	1
BLOOD_Leukemia	GSC →	+0.704	+2.948	.008	.008	3	1
BLOOD_Leukemia	ADAM30 →	+0.009	+4.247	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 597 associations by consensus.

ZIC5 by CCDC102A expression — LARGE_INTESTINE

Explore this box plot interactively →