Across TCGA patient cohorts, CCBE1 mutation is significantly associated with the RNA expression of many other genes, with 4,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCBE1-associated genes across cancer lineages are CDCA2, MAPK1IP1L, and TIMM8BP1. Each is linked with CCBE1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCBE1-to-partner and partner-to-CCBE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCBE1→partner) and Y-score (partner→CCBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.928	+3.828	<.001	<.001	3	4
UCEC	MAPK1IP1L →	+0.441	+2.021	.001	.001	3	4
LGG	TIMM8BP1 →	+0.326	+5.602	<.001	.004	3	3
UCEC	FAM168B →	+0.506	+2.010	.003	.001	3	3
UCEC	SCOC →	+0.702	+2.392	<.001	<.001	3	3
UCEC	CARNMT1 →	+0.515	+2.743	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,082 associations by consensus.

Exploration

CCBE1 survival (RNA) · tumor vs normal (RNA) · all CCBE1 data types