CCBE1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCBE1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCBE1-associated genes across cancer lineages are Ku80, PDCD4, and Annexin_VII. Each is linked with CCBE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCBE1-to-partner and partner-to-CCBE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCBE1→partner) and Y-score (partner→CCBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.258+1.594.004.04232
UCECPDCD4 →-0.450-3.169.012.01832
UCECAnnexin_VII →-0.111-1.678.037.02332
UCECATM →-0.473-2.459.006.01932
UCEC14-3-3_beta →-0.078-1.973.043.02931
UCECeIF4E →+0.189+2.584.019.00122
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

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