Across TCGA cell cohorts, CCBE1 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCBE1-associated genes across cancer lineages are GSK690693, Cyclophosphamide, and AZD5991. Each is linked with CCBE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCBE1-to-partner and partner-to-CCBE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCBE1→partner) and Y-score (partner→CCBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK690693 →	+0.638	+2.874	.007	.021	3	2
LARGE_INTESTINE	Cyclophosphamide →	+0.337	+2.649	.031	.046	3	1
LARGE_INTESTINE	AZD5991 →	+0.882	+2.871	.014	.021	2	1
LARGE_INTESTINE	Cytarabine →	+1.011	+2.655	.008	.044	1	1
LARGE_INTESTINE	Sorafenib →	+0.394	+2.777	.043	.038	1	1
LARGE_INTESTINE	CDK9_5038 →	+0.649	+3.129	.012	.014	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

CCBE1 survival (RNA) · tumor vs normal (RNA) · all CCBE1 data types