CCAR2

Across TCGA patient cohorts, CCAR2 mutation is significantly associated with the RNA expression of many other genes, with 3,880 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCAR2-associated genes across cancer lineages are RNU6-709P, CCL5, and GAPLINC. Each is linked with CCAR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCAR2-to-partner and partner-to-CCAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-709P grouped by CCAR2-low versus CCAR2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCAR2→partner) and Y-score (partner→CCAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-709P →	+0.168	+5.589	<.001	<.001	3	3
UCEC	CCL5 →	+0.788	+2.502	.001	.001	3	2
COAD	GAPLINC →	+0.775	+3.210	<.001	.009	3	2
CESC	SIGLEC27P →	+0.031	+5.589	<.001	<.001	3	2
UCEC	IGHD3-16 →	+0.872	+1.742	<.001	<.001	3	2
CESC	RN7SKP152 →	+0.093	+3.984	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

RNU6-709P by CCAR2 expression — CESC

Explore this box plot interactively →