CCAR2

Across TCGA cell cohorts, CCAR2 mutation is significantly associated with the RNA expression of many other genes, with 1,084 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCAR2-associated genes across cancer lineages are OR11H6, H1-8, and CYP2A13. Each is linked with CCAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCAR2-to-partner and partner-to-CCAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H6 grouped by CCAR2-low versus CCAR2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCAR2→partner) and Y-score (partner→CCAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR11H6 →	+0.026	+4.321	<.001	.009	3	1
CNS	H1-8 →	+0.022	+5.357	<.001	.001	3	1
CNS	CYP2A13 →	+0.043	+5.044	<.001	.001	3	1
STOMACH	TFDP3 →	+0.022	+3.632	<.001	.009	3	1
STOMACH	TRARG1 →	+0.022	+3.830	<.001	.005	3	1
STOMACH	GAGE12F →	+2.076	+4.280	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,084 associations by consensus.

OR11H6 by CCAR2 expression — CNS

Explore this box plot interactively →