Across TCGA patient cohorts, CC2D2B mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CC2D2B-associated genes across cancer lineages are PCNA, eIF4E, and MEK1. Each is linked with CC2D2B in more than 2 cancer types. Because this analysis shows association rather than direction, both CC2D2B-to-partner and partner-to-CC2D2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CC2D2B→partner) and Y-score (partner→CC2D2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.229	+2.000	.002	.003	3	3
UCEC	eIF4E →	+0.159	+3.335	.032	.005	3	2
UCEC	MEK1 →	+0.479	+2.874	<.001	<.001	3	2
UCEC	PKC-b-II_pS660 →	-0.244	-1.906	.012	.015	3	2
UCEC	STAT3_pY705 →	-0.446	-2.392	<.001	<.001	3	2
UCEC	c-Met_pY1235 →	+0.058	+1.362	.026	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

CC2D2B survival (RNA) · tumor vs normal (RNA) · all CC2D2B data types