CC2D1A

Across TCGA pan-cancer cohorts, CC2D1A mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CC2D1A’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CC2D1A mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CC2D1A is over-expressed in tumor, although a few such as COAD and HNSC show the opposite, repressed pattern.

COAD, HNSC, and LSCC are the cancer types where CC2D1A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CC2D1A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.131	<.001	10	view →
HNSC	Male	All	−0.230	<.001	8	view →
LSCC	Male	All	+0.099	.004	2	view →
CCRCC	All	All	+0.061	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CC2D1A–COAD

Open the COAD breakdown →