CBY1

Across TCGA patient cohorts, CBY1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBY1-associated genes across cancer lineages are PARPBP, MYBL2, and E2F1. Each is linked with CBY1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CBY1-to-partner and partner-to-CBY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBY1 versus PARPBP in OV, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBY1→partner) and Y-score (partner→CBY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARPBP →	-1.192	-2.687	.004	<.001	3	5
UCEC	MYBL2 →	-1.306	-0.344	<.001	.003	3	4
BRCA	E2F1 →	-1.176	-0.401	.001	<.001	3	4
OV	OIP5 →	-1.407	-2.792	.002	.001	3	4
UCEC	CCNF →	-0.906	-0.403	<.001	.003	3	4
UCEC	IGFBP7 →	+1.061	+0.735	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,657 associations by consensus.

CBY1 vs PARPBP — OV

Explore this scatter interactively →