CBX8

Across TCGA patient cohorts, CBX8 protein abundance is significantly associated with the RNA expression of many other genes, with 20,220 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CBX8-associated genes across cancer lineages are CLEC7A, NAT9, and FLI1. Each is linked with CBX8 in more than 8 cancer types. Because this analysis shows association rather than direction, both CBX8-to-partner and partner-to-CBX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX8 versus CLEC7A in GBM, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX8→partner) and Y-score (partner→CBX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLEC7A →	-0.999	-0.575	<.001	<.001	3	9
HNSC	NAT9 →	+0.834	+0.416	.004	<.001	3	8
LSCC	FLI1 →	-0.632	-0.358	<.001	<.001	3	8
GBM	LAIR1 →	-1.129	-0.646	<.001	<.001	3	8
OV	ABI3 →	-0.831	-0.371	.002	.002	3	7
OV	CXorf21 →	-0.817	-0.317	.002	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,220 associations by consensus.

CBX8 vs CLEC7A — GBM

Explore this scatter interactively →