CBX3P4

Across TCGA pan-cancer cohorts, CBX3P4 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CBX3P4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CBX3P4 RNA is repressed in tumor relative to normal tissue. In most cancer types CBX3P4 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where CBX3P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBX3P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.280	<.001	9	view →
KIRC	Male	II,III,IV	−0.172	.003	5	view →
LIHC	All	All	+0.076	.002	5	view →
CHOL	All	All	+0.594	<.001	4	view →
COAD	All	All	+0.184	.006	4	view →
BRCA	All	All	+0.154	.002	4	view →
HNSC	Male	III,IV	+0.148	.013	4	view →
READ	All	All	+0.238	.008	2	view →
ESCA	All	All	−0.158	.009	2	view →
LUSC	All	All	+0.123	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CBX3P4–THCA

Open the THCA breakdown →