CBX3P3

Across TCGA pan-cancer cohorts, CBX3P3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CBX3P3’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CBX3P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CBX3P3 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

UCEC, ESCA, and PRAD are the cancer types where CBX3P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBX3P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	+0.155	.030	4	view →
ESCA	All	II,III,IV	+0.899	.020	2	view →
PRAD	All	All	+0.199	.034	2	view →
BRCA	All	All	+0.135	.043	2	view →
HNSC	Male	II,III,IV	+0.039	.041	2	view →
LIHC	All	All	+0.019	.021	2	view →
STAD	Male	IV	−0.220	.047	1	view →
KICH	All	II,III,IV	+0.034	.040	1	view →
KIRC	Male	All	+0.034	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CBX3P3–UCEC

Open the UCEC breakdown →