CBX3

Across TCGA patient cohorts, CBX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,735 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX3-associated proteins across cancer lineages are PUS7, BZW2, and POLD2. Each is linked with CBX3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CBX3-to-partner and partner-to-CBX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX3 versus PUS7 in HNSC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX3→partner) and Y-score (partner→CBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PUS7 →	+0.383	+0.792	.001	.003	3	8
LUAD	BZW2 →	+0.529	+0.635	<.001	<.001	3	8
LSCC	POLD2 →	+0.300	+0.516	.002	<.001	3	8
LSCC	HAT1 →	+0.397	+0.468	.002	.001	3	7
LUAD	MCM2 →	+0.563	+0.399	<.001	<.001	3	7
LSCC	MCM3 →	+0.700	+0.642	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,735 associations by consensus.

CBX3 vs PUS7 — HNSC

Explore this scatter interactively →