CBX2

Across TCGA patient cohorts, CBX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,241 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX2-associated proteins across cancer lineages are SMARCA4, RRP36_S73, and SMC2. Each is linked with CBX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CBX2-to-partner and partner-to-CBX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX2 versus SMARCA4 in GBM, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX2→partner) and Y-score (partner→CBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMARCA4 →	+0.411	+1.069	<.001	<.001	3	8
BRCA	RRP36_S73 →	+0.792	+1.735	<.001	<.001	3	7
GBM	SMC2 →	+0.660	+0.944	<.001	<.001	3	7
LSCC	WDHD1 →	+0.676	+1.103	<.001	.004	3	7
BRCA	CDYL_S216 →	+0.765	+1.066	<.001	<.001	3	7
BRCA	CEBPZ →	+0.383	+1.217	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,241 associations by consensus.

CBX2 vs SMARCA4 — GBM

Explore this scatter interactively →