CBX2

Across TCGA patient cohorts, CBX2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX2-associated genes across cancer lineages are GINS1, DBN1, and DNMT3A. Each is linked with CBX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CBX2-to-partner and partner-to-CBX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX2 versus GINS1 in LUAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX2→partner) and Y-score (partner→CBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GINS1 →	+1.092	+0.828	<.001	<.001	3	6
BRCA	DBN1 →	+0.706	+0.685	<.001	<.001	3	6
OV	DNMT3A →	+0.952	+1.336	<.001	<.001	3	6
OV	BEND3 →	+0.721	+1.238	.002	.001	3	6
CCRCC	KLHL23 →	+1.078	+0.925	.001	.001	3	6
BRCA	MEX3A →	+1.696	+1.073	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,410 associations by consensus.

CBX2 vs GINS1 — LUAD

Explore this scatter interactively →