CBX1P3

Across TCGA pan-cancer cohorts, CBX1P3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CBX1P3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CBX1P3 RNA is repressed in tumor relative to normal tissue. In most cancer types CBX1P3 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, BRCA, and KICH are the cancer types where CBX1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBX1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.194	<.001	8	view →
BRCA	Female	All	+0.174	.003	6	view →
KICH	Male	All	−0.350	.001	4	view →
KIRP	All	All	−0.110	.026	4	view →
THCA	Female	All	−0.074	.001	4	view →
LUAD	Female	II,III,IV	+0.069	.016	3	view →
LIHC	All	II,III,IV	+0.033	.019	3	view →
PRAD	All	All	−0.079	.010	2	view →
LUSC	Female	III,IV	+0.180	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CBX1P3–KIRC

Open the KIRC breakdown →