CBWD5

Across TCGA pan-cancer cohorts, CBWD5 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated CBWD5 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CBWD5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CBWD5 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

ACC, BRCA, and ESCA are the cancer types where CBWD5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.255	0.645	<.001	72	view →
BRCA	OS	Tertile	III,IV	0.935	0.758	<.001	64	view →
ESCA	DFS	Quartile	III,IV	0.209	0.721	<.001	53	view →
SKCM	DFS	Quartile	II,III,IV	0.407	0.190	.002	47	view →
COAD	DFS	Median	All	0.590	0.781	<.001	40	view →
KIRC	DFS	Quartile	IV	0.256	0.638	.002	32	view →
UVM	DFS	Quartile	III,IV	0.226	1.000	<.001	27	view →
CHOL	OS	Median	All	0.866	0.336	<.001	24	view →
PRAD	DFS	Median	All	0.684	0.885	<.001	24	view →
MESO	DFS	Quartile	III,IV	0.171	0.741	.010	20	view →
PAAD	DFS	Quartile	All	0.548	0.250	.022	18	view →
HNSC	DFS	Tertile	III,IV	0.604	0.739	.011	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

CBWD5–ACC (DFS)

Open the ACC breakdown →