CBWD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CBWD1 mutation is significantly associated with the RNA expression of many other genes, with 3,411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBWD1-associated genes across cancer lineages are REXO1L8P, ATP2B2-IT2, and RNA5SP443. Each is linked with CBWD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CBWD1-to-partner and partner-to-CBWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REXO1L8P grouped by CBWD1-low versus CBWD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD1→partner) and Y-score (partner→CBWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADREXO1L8P →+0.036+6.142<.001<.00134
SARCATP2B2-IT2 →+0.111+5.778<.001.00332
BRCARNA5SP443 →+0.420+5.122<.001.00832
BRCASNORD114-18 →+0.682+6.639<.001.00132
BLCASNORD115-21 →+0.432+7.640<.001.00932
UCECRNA5SP436 →+0.284+2.937<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,411 associations by consensus.

REXO1L8P by CBWD1 expression — COAD

Box plot of REXO1L8P in CBWD1-low vs CBWD1-high samples in COAD.

Explore this box plot interactively →

Exploration