CBWD1

Across TCGA cell cohorts, CBWD1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CBWD1-associated genes across cancer lineages are OR10A3, MDGA2, and OR1L6. Each is linked with CBWD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD1-to-partner and partner-to-CBWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A3 grouped by CBWD1-low versus CBWD1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD1→partner) and Y-score (partner→CBWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10A3 →	+0.062	+5.029	<.001	.006	3	1
LARGE_INTESTINE	MDGA2 →	+0.226	+3.854	<.001	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	RBMY1F →	+0.221	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10A3 by CBWD1 expression — LUNG_SCLC

Explore this box plot interactively →