CBWD1

Across TCGA cell cohorts, CBWD1 mutation is significantly associated with the mutation status of many other genes, with 1,420 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CBWD1-associated genes across cancer lineages are SLC2A4, ARSH, and SF3A1. Each is linked with CBWD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD1-to-partner and partner-to-CBWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC2A4 grouped by CBWD1-low versus CBWD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD1→partner) and Y-score (partner→CBWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SLC2A4 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	ARSH →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	SF3A1 →	+5.772	+5.772	.002	.002	1	2
LUNG_NSCLC_LUAD	ZNF160 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	RPH3A →	+4.772	+5.339	.004	.004	1	2
LUNG_SCLC	XAB2 →	+5.066	+4.502	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,420 associations by consensus.

SLC2A4 by CBWD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →