CBSL

Across TCGA patient cohorts, CBSL RNA expression is significantly associated with the go_rna of many other GO terms, with 6,616 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CBSL-associated GO terms across cancer lineages are GMP biosynthetic process, Mitotic recombination, and Positive regulation of attachment of spindle microtubules to kinetochore. Each is linked with CBSL in more than 12 cancer types. Because this analysis shows association rather than direction, both CBSL-to-partner and partner-to-CBSL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP biosynthetic process grouped by CBSL-low versus CBSL-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBSL→partner) and Y-score (partner→CBSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	GMP biosynthetic process →	+0.062	+0.165	<.001	<.001	3	13
LUSC	Mitotic recombination →	+0.028	+0.319	<.001	<.001	3	13
GBM	Positive regulation of attachment of spindle microtubules to kinetochore →	+0.063	+0.652	<.001	.001	2	13
STAD	Negative regulation of DNA replication →	+0.033	+0.104	<.001	<.001	3	12
LUAD	Regulation of cytokinesis →	+0.026	+0.400	<.001	<.001	3	12
TGCT	Establishment of mitotic spindle localization →	+0.042	+0.582	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,616 associations by consensus.

GMP biosynthetic process by CBSL expression — STAD

Explore this box plot interactively →