Across TCGA pan-cancer cohorts, CBR4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CBR4 data layer compared with 24 for mass-spec protein.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher CBR4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CBR4 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.
COAD, CCRCC, and PDAC are the cancer types where CBR4 mass-spec protein most reproducibly stratifies survival.