CBR4

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CBR4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CBR4 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CBR4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CBR4 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where CBR4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianII,III,IV1.0000.910.01142view →
CCRCCOSMedianAll1.0000.679.01315view →
PDACDFSQuartileAll0.4320.238.0199view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CBR4–COAD (DFS)

Kaplan–Meier survival curve for CBR4 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration