CBR4

Across TCGA patient cohorts, CBR4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,635 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CBR4-associated genes across cancer lineages are HSD17B8, SYNPR-AS1, and SYBU. Each is linked with CBR4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CBR4-to-partner and partner-to-CBR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBR4 versus HSD17B8 in UCEC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR4→partner) and Y-score (partner→CBR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSD17B8 →	+1.307	+0.500	<.001	<.001	2	7
BRCA	SYNPR-AS1 →	+1.102	+0.678	<.001	<.001	3	6
BRCA	SYBU →	+0.955	+0.474	<.001	<.001	3	5
BRCA	TKFC →	+0.560	+0.554	.003	<.001	3	5
HNSC	MYLIP →	+0.669	+0.381	.003	.004	3	5
COAD	DSE →	-0.563	-0.383	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,635 associations by consensus.

CBR4 vs HSD17B8 — UCEC

Explore this scatter interactively →