CBR3

Across TCGA patient cohorts, CBR3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,068 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CBR3-associated genes across cancer lineages are GLI1, GSN, and SH3RF2. Each is linked with CBR3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CBR3-to-partner and partner-to-CBR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBR3 versus GLI1 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR3→partner) and Y-score (partner→CBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GLI1 →	+1.153	+0.383	.003	<.001	3	5
BRCA	GSN →	+0.619	+0.494	.001	<.001	3	5
LUAD	SH3RF2 →	+0.860	+0.336	.002	.008	3	5
OV	AHR →	+0.771	+0.713	<.001	.002	3	4
OV	MGP →	+0.986	+0.532	<.001	<.001	3	4
UCEC	PTGFR →	+0.933	+0.347	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,068 associations by consensus.

CBR3 vs GLI1 — GBM

Explore this scatter interactively →