CBR3

Across TCGA patient cohorts, CBR3 mutation is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBR3-associated genes across cancer lineages are MIR4748, RNU6-1097P, and RNU1-17P. Each is linked with CBR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBR3-to-partner and partner-to-CBR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4748 grouped by CBR3-low versus CBR3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR3→partner) and Y-score (partner→CBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4748 →	+0.618	+2.479	.001	.001	3	2
LUAD	RNU6-1097P →	+0.253	+7.930	<.001	.008	3	2
UCEC	RNU1-17P →	+0.222	+2.476	<.001	.009	3	2
COAD	MTCO2P23 →	+0.637	+6.721	<.001	<.001	3	2
COAD	RNU7-50P →	+1.300	+5.212	<.001	.007	3	2
BLCA	RNU6-166P →	+0.343	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

MIR4748 by CBR3 expression — UCEC

Explore this box plot interactively →