CBR3

Across TCGA cell cohorts, CBR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,669 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CBR3-associated GO terms across cancer lineages are Phylloquinone catabolic process, Vitamin K catabolic process, and Glucocorticoid metabolic process. Each is linked with CBR3 in more than 15 cancer types. Because this analysis shows association rather than direction, both CBR3-to-partner and partner-to-CBR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phylloquinone catabolic process grouped by CBR3-low versus CBR3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR3→partner) and Y-score (partner→CBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Phylloquinone catabolic process →	+1.709	+2.515	<.001	<.001	3	16
KIDNEY	Vitamin K catabolic process →	+1.709	+2.515	<.001	<.001	3	16
STOMACH	Glucocorticoid metabolic process →	+0.198	+1.253	.001	.003	3	10
CNS	Positive regulation of protein processing →	+0.138	+1.573	.004	.001	3	9
BREAST	Fat-soluble vitamin catabolic process →	+1.068	+1.151	<.001	.004	3	9
CNS	Positive regulation of protein maturation →	+0.136	+1.626	.005	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,669 associations by consensus.

Phylloquinone catabolic process by CBR3 expression — KIDNEY

Explore this box plot interactively →