CBR3-AS1

Across TCGA pan-cancer cohorts, CBR3-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CBR3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CBR3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CBR3-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

KIRC, UVM, and PAAD are the cancer types where CBR3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	III,IV	0.360	0.555	.001	97	view →
UVM	DFS	Median	II,III,IV	0.338	0.721	.003	55	view →
PAAD	OS	Median	All	0.517	0.252	<.001	49	view →
MESO	OS	Quartile	All	0.238	0.498	.002	33	view →
LIHC	OS	Quartile	II,III,IV	0.212	0.672	.001	28	view →
CHOL	DFS	Tertile	II,III,IV	0.146	0.607	.006	28	view →
BRCA	DFS	Tertile	All	0.403	0.597	.003	27	view →
HNSC	OS	Median	All	0.818	0.717	.004	23	view →
LUAD	OS	Quartile	All	0.867	0.758	.012	18	view →
ESCA	DFS	Quartile	II,III,IV	0.180	0.483	.008	15	view →
BLCA	OS	Quartile	III,IV	0.748	0.535	.010	14	view →
SKCM	DFS	Median	All	0.668	0.555	.010	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CBR3-AS1–KIRC (DFS)

Open the KIRC breakdown →