CBR1

Across TCGA patient cohorts, CBR1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,294 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBR1-associated genes across cancer lineages are AKR1C3, CBR3, and LDHD. Each is linked with CBR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CBR1-to-partner and partner-to-CBR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBR1 versus AKR1C3 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR1→partner) and Y-score (partner→CBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1C3 →	+3.272	+0.850	<.001	<.001	3	5
LSCC	CBR3 →	+1.247	+0.961	<.001	<.001	3	5
OV	LDHD →	+0.860	+0.211	<.001	.009	3	5
LSCC	AKR1B10 →	+3.762	+0.915	<.001	<.001	3	5
UCEC	PLAAT2 →	+1.306	+0.402	<.001	.001	3	4
LSCC	AKR1C2 →	+3.531	+0.978	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,294 associations by consensus.

CBR1 vs AKR1C3 — LSCC

Explore this scatter interactively →