CBR1

Across TCGA patient cohorts, CBR1 mutation is significantly associated with the RNA expression of many other genes, with 1,848 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBR1-associated genes across cancer lineages are RN7SL591P, MRPS35P2, and LINC01848. Each is linked with CBR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBR1-to-partner and partner-to-CBR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL591P grouped by CBR1-low versus CBR1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBR1→partner) and Y-score (partner→CBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL591P →	+0.265	+5.392	.003	.002	3	2
COAD	MRPS35P2 →	+0.774	+5.251	<.001	.003	3	2
SKCM	LINC01848 →	+0.317	+4.993	<.001	.002	3	2
UCEC	RNA5SP394 →	+0.136	+3.038	.006	.006	3	2
SKCM	SLC7A2-IT1 →	+0.118	+4.730	<.001	.003	3	1
UCEC	NCMAP-DT →	+0.243	+2.415	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,848 associations by consensus.

RN7SL591P by CBR1 expression — COAD

Explore this box plot interactively →