CBLN2

Across TCGA patient cohorts, CBLN2 mutation is significantly associated with the RNA expression of many other genes, with 3,789 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBLN2-associated genes across cancer lineages are MAGOH, NUDCD2, and RAD54L. Each is linked with CBLN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CBLN2-to-partner and partner-to-CBLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGOH grouped by CBLN2-low versus CBLN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN2→partner) and Y-score (partner→CBLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAGOH →	+0.283	+2.732	.008	.003	3	3
UCEC	NUDCD2 →	+0.494	+2.776	<.001	<.001	3	3
UCEC	RAD54L →	+0.810	+3.807	<.001	<.001	3	3
UCEC	PRIM1 →	+0.644	+2.545	<.001	<.001	3	3
UCEC	BYSL →	+0.328	+2.343	.009	.003	3	3
UCEC	MTFR2 →	+0.509	+2.069	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,789 associations by consensus.

MAGOH by CBLN2 expression — UCEC

Explore this box plot interactively →