CBLL1

Across TCGA patient cohorts, CBLL1 mutation is significantly associated with the RNA expression of many other genes, with 1,554 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBLL1-associated genes across cancer lineages are BOLA3P3, RPS15P9, and IGLV5-48. Each is linked with CBLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLL1-to-partner and partner-to-CBLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BOLA3P3 grouped by CBLL1-low versus CBLL1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLL1→partner) and Y-score (partner→CBLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	BOLA3P3 →	+0.471	+3.854	<.001	.004	3	2
BLCA	RPS15P9 →	+0.623	+3.813	.002	.005	3	2
SKCM	IGLV5-48 →	+1.009	+2.747	.001	.008	3	2
UCEC	NUTF2P8 →	+0.100	+2.398	<.001	.004	3	2
UCEC	RNA5SP412 →	+0.442	+2.074	.003	.004	3	2
LUAD	FAM197Y5 →	+0.039	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,554 associations by consensus.

BOLA3P3 by CBLL1 expression — BLCA

Explore this box plot interactively →